The WCN’ 23 was built on three themes Kidney Failure (KF), Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI). This symposium on AKI consists of seven sessions covering the latest themes on approach to intervention, epidemiology, drug induced AKI, novel technologies, advanced PD, renal replacement therapy, and biomarkers.
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A Multifaceted Approach to AKI Intervention
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This session will cover the several aspects around the detection and care of patients at risk and diagnosed with AKI. While the traditional, consensus definition of AKI involves measurement of serum creatinine and urine output however increasingly in both high and low resources settings new methods to assess AKI have been used. This session will cover the use of machine learning risk scores as well as other point of care devices (e.g. point of care creatinine and salivary urea nitrogen) to detect AKI. Additionally, we will discuss the use of other point of care devices that can help in the assessment and care of AKI patients (e.g. point of care ultrasound (POCUS)). Lastly this session will discuss the clinical utility of AKI care bundles and the mixed results that have been reported when these multifaceted bundles have been studied in randomized controlled trials.
Changing Epidemiology and Outcomes of AKI. ISN-Indian Society of Nephrology Joint Session
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This session will focus on a global perspective of AKI, including AKI in special settings such as natural disasters, AKI diagnoses and management in tropical and resource limited countries, as well as global AKI incidence and management during the Covid 19 pandemic.
Drug-induced AKI
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Drug-induced AKI is an important and preventable cause of AKI, both in community and hospital acquired-AKI. This session will cover a comprehensive overview of evaluation, recognition, management and prevention of drug-induced AKI in adults and children, the role of electronic alerts for identification of high-risk nephrotoxicity patients and early diagnosis of kidney function deterioration associated to drugs in the hospital setting and will discuss a escalating problem, the issue of drugs nephrotoxicity in onconephrology.
Novel Technologies to Improve Our Understanding of AKI
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Although currently few therapeutic interventions for human AKI, new technologies are ready to revolutionize to help to elucidate the pathophysiology, providing new opportunities for early detection and novel interventions. In this session, we will discuss new imaging techniques, -omic studies especially transcriptomics, regenerative medicine as well as optogenetics as a novel tool for understanding neural circuits with respect to the control of renal inflammation in AKI. These strategies hold tremendous promise for effective bench-to-bedside translation of novel discoveries that will change the current dismal prognosis of human AKI.
Promotion of Advanced PD. ISN-ISPD Joint Session
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This session aims to improve the perception on PD through different talks covering home therapy, young AKI patients' experience with PD and the features of PD, especially its low infection rate and economic characteristics.
Learning Objectives:
To shift the stereotype perception on PD via evidence in order to raise general nephrologists' awareness in practicing PD, specially for people living in lower income countries.
Renal Replacement Therapy In AKI
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This session is designed to provide participants with the latest evidence regarding the effective utilization of Renal Replacement Therapy (RRT) in critically ill patients. The focus of the session is on timing of initiation, modality, and dose. In addition, this session will cover the role of RRT with other organ support therapies.
Learning Objectives:
Identify key studies regarding optimal timing of RRT initiation in critically ill patients. Understand key issues regarding choice of modality for AKI in the ICU. Review RRT dosing recommendations and the challenges in delivering dose. Discuss the role of RRT with other organ support therapies in critically ill patients with multiple organ dysfunction.
Risks and Management of AKI Biomarkers
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This session aims to cover a number of very important aspects relating to the acute kidney injury (AKI) Biomarkers. Implement biomarkers in the clinical workflow to improve AKI and RRT care session will demonstrate how to apply novel AKI biomarkers in AKI clinical practice from prediction persistent AKI, AKI outcome, and guiding renal replacement therapy initiation. Urinary sediments in AKI session will describe and discuss the value of utilizing urine microscopy in the diagnosis of AKI. Finally, there will be an update in novel biomarkers in AKI which has been recently discovered.
Learning Objectives:
An application for AKI biomarkers in clinical practice. A utilization urine microscopy in the management of AKI. An update on current and recent discovered AKI biomarkers.