ISN Video Animation Series

Recorded On: 04/21/2023

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Selected monthly KI and KI Reports abstracts converted into bite-size video animations

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KI
Targeted-release Budesonide Modifies Key Pathogenic Biomarkers in Immunoglobulin A Nephropathy: Insights from the NEFIGAN trial
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Open to view video.
Complement Alternative Pathway Determines Disease Susceptibility and Severity in Antineutrophil Cytoplasmic Antibody (ANCA)–associated Vasculitis
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Open to view video.
Effects of Newer Kidney Protective Agents on Kidney Endpoints Provide Implications for Future Clinical Trials
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Open to view video.
The Genetic Landscape and Clinical Spectrum of Nephronophthisis and Related Ciliopathies
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Open to view video.
A Nationwide Cohort Study Comparing the Effectiveness of Diuretics and Calcium Channel Blockers on Top of Renin-angiotensin System Inhibitors on Chronic Kidney Disease Progression and Mortality
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Open to view video.
Systems Analyses of the Fabry Kidney Transcriptome and its Response to Enzyme Replacement Therapy Identified and Cross-validated Enzyme Replacement Therapy-resistant Targets Amenable to Drug Repurposing
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Introduction of a Novel Chimeric Active Immunization Mouse Model of Phospholipase A2 Receptor 1-associated Membranous Nephropathy
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Open to view video.
A Comprehensive Description of Kidney Disease Progression After Acute Kidney Injury From a Prospective, Parallel-group Cohort Study
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Zinc finger protein 24-dependent transcription factor SOX9 up-regulation protects tubular epithelial cells during acute kidney injury
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Transitional B cell Cytokines Risk Stratify Early Borderline Rejection After Renal Transplantation
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A Novel Direct Adenosine Monophosphate Kinase Activator Ameliorates Disease Progression in Preclinical Models of Autosomal Dominant Polycystic Kidney Disease
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Open to view video.
Results From Part A of the Multi-center, Double-blind, Randomized, Placebo-controlled NefIgArd Trial, Which Evaluated Targeted-release Formulation of Budesonide for the Treatment of Primary Immunoglobulin A Nephropathy
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Open to view video.
Seven Novel Putative Antigens in Membranous Nephropathy and Membranous Lupus Nephritis Identified by Mass Spectrometry
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Open to view video.
Association Between Cholinesterase Inhibitors and Kidney Function Decline in Patients with Alzheimer's Dementia
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Open to view video.
Incidence of New Onset Glomerulonephritis After SARS-CoV-2 mRNA Vaccination is not Increased
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Open to view video.
A Randomized Controlled Pilot Trial of Anakinra for Hemodialysis Inflammation
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Open to view video.
Efficacy of Corticosteroids in Infection-related Glomerulonephritis – A Randomized Controlled Trial
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A Tool for Decision-making in Kidney Transplant Candidates With Poor Prognosis to Receive Deceased Donor Transplantation in the United States
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Alternative Component Pathway Inhibition with Ibtacopan for the Treatment of C3 Glomerulopathy - Study Design of the APPEAR -C3G Trial
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Open to view video.
Preemptive Simultaneous Pancreas Kidney Transplantation has Survival Benefit to Patient
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Chronic Lithium Therapy and Urine Concentration Ability in Individuals With Bipolar Disorder
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A Glomerular Transcriptomic Landscape of Apolipoprotein L1 in Black Patients with Focal Segmental Glomerulosclerosis
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Calculated Versus Measured Albumin-creatinine Ratio to Predict Kidney Failure and Death in People With Chronic Kidney Disease
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Association of Cardiac Autonomic Neuropathy Assessed by Heart Rate Response During Exercise with Intradialytic Hypotension and Mortality in Hemodialysis Patients
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Open to view video.
Clinical Outcomes from the Assessing Donor-derived Cell-free DNA Monitoring Insights of Kidney Allografts with Longitudinal Surveillance (ADMIRAL) Study
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Open to view video.
Safety, Pharmacodynamics, and Exposure-response Modeling Results From a First Human Phase 1 Study of Nedosiran (PHYOX1) in Primary Hyperoxaluria
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Open to view video.
A Prospective Observational Study for Justification, safety, and Efficacy of a Third dose of mRNA Vaccine in Patients Receiving Maintenance Hemodialysis
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Open to view video.
The Cell Membrane Repair Protein MG53 Modulates Transcription Factor NF-kb Signaling to Control Kidney Fibrosis
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Combination Treatment with Rituximab, Low-dose Cyclophosphamide & Plasma Exchange for Severe ANCA-associated Vasculitis
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Open to view video.
A Mathematical Estimation of the Physical Forces Driving Podocyte Detachment
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KIR
Efficacy and Safety of Iptacopan in Patients with C3 Glomerulopathy
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Open to view video.
Optimization of Rituximab Therapy in Adult patients with PLA2R1-associated Membranous Nephropathy with Artificial Intelligence
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Open to view video.
Effect of Immunosuppressive Treatments on Kidney Outcomes after Gross Hematuria-Related Acute Kidney Injury in Older Patients With IgA Nephropathy
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Open to view video.
Neurodevelopment After Neonatal Acute Kidney Injury in Very Preterm-Birth Children
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Open to view video.
Anatomo-Genomic Confrontation: Unraveling Genomic Basis of Histologically Undetermined Kidney Diseases
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Open to view video.
Clinical Safety and Efficacy of Pegcetacoplan in a Phase 2 Study of Patients with C3 Glomerulopathy and Other Complement-Mediated Glomerular Diseases
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Open to view video.
Randomization Trial on the Effects of Dialysate Potassium Concentration on Intradialytic Hypertension
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Open to view video.
Epigenome-Wide Meta-Analysis Reveals Differential DNA Methylation Associated With Estimated Glomerular Filtration Rate Among African American Men With HIV
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D-Asparagine is an Ideal Endogenous Molecule for Measuring Glomerular Filtration Rate
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Antibody Guided Therapy in PLA2R-associated Membranous Nephropathy
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Renal Recovery for Patients with Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis and Low Estimated GFR in the ADVOCATE Trial of Avacopan
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Open to view video.
Associations of Serum and Dialysate Potassium Concentrations With Incident Atrial Fibrillation in a Cohort Study of Older US Persons Initiating Hemodialysis for Kidney Failure
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Open to view video.
Persistent isolated C3 Hypocomplementemia as a Strong Predictor of End-stage Kidney Disease in Lupus Nephritis
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High-volume Hemodiafiltration and Cool Hemodialysis Have a Beneficial Effect on Intradialytic Hemodynamics: a Randomized Cross-over Trial of Four Intermittent Dialysis Strategies
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Open to view video.
Neutrophil Gelatinase-associated Lipocalin is Elevated in Children With Acute Kidney Injury and Sickle Cell Anemia, and Predicts Mortality
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Open to view video.
Randomized Phase II JANUS Study of Atacicept in Patients With Immunoglobulin A Nephropathy and Persistent Proteinuria
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Open to view video.
Comparison of Complement Pathway Activation in Autoimmune Glomerulonephritis
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Open to view video.
Depressive Symptoms at Kidney Transplant Evaluation and Access to the Kidney Transplant Waitlist
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Open to view video.
The Density of Renal Lymphatics Correlates With Clinical Outcomes in IgA
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Open to view video.
Kidney function, Kidney Replacement Therapy and Mortality in Men and Women
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Open to view video.
Urine Single-Cell RNA-Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures
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Open to view video.
Later Response to Corticosteroids in Adults with Primary FSGS is Associated with Favorable Outcomes
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Open to view video.
NAD+ Biosynthetic Impairment and Urinary Metabolomic Alterations Observed in Hospitalized Adults with COVID-19 Related Acute Kidney Injury
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Open to view video.
The COVID-19 Pandemic Identifies Significant Global Inequities in Hemodialysis Care in Lower-Middle Income Countries An ISN/DOPPS Survey
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Open to view video.