ISN Newly Independent States and Russia Regional Board Webinar: Could your region be a CKDu hotspot? Identifying and Understanding the Epidemic

This webinar will introduce the problem of CKDu, a form of chronic kidney disease primarily affecting young men in rural agricultural communities, with no identifiable link to common causes of CKD. We aim to bring together the leading experts of the ISN International Consortium of CKDu Collaborators (i3C) to share their expertise with the kidney healthcare providers from the NIS and Russia Region. Our speakers will present an overview of the epidemiology, potential etiological factors, clinical spectrum, and management, as well as research methodologies applicable to assess CKDu prevalence.

Learning objectives:

- Understand the clinical presentation and etiology of CKDu
- Explore the diagnostic approaches in the limited resource
- Discuss research methodologies to assess CKDu prevalence

Further reading:

• Wijewickrama E, Caplin B. Heat Exposure and Short-Term Changes in Kidney Biomarkers: Answers to the CKD of Unknown Etiology Conundrum? Kidney Int Rep. 2025 Jun 18;10(8):2527-2529. doi: 10.1016/j.ekir.2025.06.011.
• Caplin B, Yang CW, Anand S, et al; International Society of Nephrology’s International Consortium of Collaborators on Chronic Kidney Disease of Unknown Etiology (i3C). The International Society of Nephrology’s International Consortium of Collaborators on Chronic Kidney Disease of Unknown Etiology: report of the working group on approaches to population-level detection strategies and recommendations for a minimum dataset. Kidney Int. 2019 Jan;95(1):4-10. doi: 10.1016/j.kint.2018.08.019. Erratum in: Kidney Int. 2019 Apr;95(4):997-998.
• Wijewickrama ES, Gunawardena N, Jayasinghe S, Herath C. CKD of Unknown Etiology (CKDu) in Sri Lanka: A Multilevel Clinical Case Definition for Surveillance and Epidemiological Studies. Kidney Int Rep. 2019 Apr 3;4(6):781-785. doi: 10.1016/j.ekir.2019.03.020.
• Caplin B, Jakobsson K, Glaser J et al. International Collaboration for the Epidemiology of eGFR in Low and Middle Income Populations – Rationale and core protocol for the Disadvantaged Populations eGFR Epidemiology Study (DEGREE). BMC Nephrol. 2017;18(1):1. https://doi.org/10.1186/s12882...