ISN-ACT Trial List: October 2018
ISN Academy. ISN-ACT . 10/09/18; 233833; 4712 Topic: General Nephrology

Access to Premium content is an ISN members and ISN Academy Premium Users benefit.

Click Here to become an ISN Member.

If you prefer to benefit from free limited access to the ISN Academy, create your account Here.

Discussion Forum (0)
Rate & Comment (0)
Once a month, the ISN-ACT (Advancing Clinical Trials) team collects and publishes a list of important nephrology trials from the latest medical literature. Each trial is reviewed in context and their risk of bias in seven key areas assessed. This month, we reviewed the following trials:

- Febuxostat does not slow decline in renal function in Japanese RCT
Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial
Am J Kidney Dis. 2018 Aug 31. pii: S0272-6386(18)30834-5

- Are two jabs better than one for transplant recipients?
Immunogenicity and safety of double versus standard dose of the seasonal influenza vaccine in solid-organ transplant recipients: A randomized controlled trial
Mombelli, et al. Vaccine. 2018;36(41):6163-6169

- Small study raises question mark over drug-coated balloon angioplasty in AVF
Drug-Coated Versus Plain Balloon Angioplasty In Arteriovenous Fistulas: A Randomized, Controlled Study With 1-Year Follow-Up (The Drecorest Ii-Study)
Björkman, et al. Scand J Surg. 2018 Sep 5:1457496918798206

- Calcium channel blockers may have an edge over thiazides and ACE inhibitors in essential hypertension in Ethiopia
Comparative effectiveness of antihypertensive drugs prescribed in Ethiopian healthcare practice: A pilot prospective, randomized, open label study
Mengesha, et al. PLoS One. 2018;13(9):e0203166

- More evidence in favour of rising tide of peritoneal dialysis in the ICU
Acute Kidney Injury in Critically Ill Patients: A Prospective Randomized Study of Tidal Peritoneal Dialysis Versus Continuous Renal Replacement Therapy
Al-Hwiesh, et al. Ther Apher Dial 2018;22(4):371–379

- Higher dialysate magnesium lowers serum calcification propensity
The Effect of Increasing Dialysate Magnesium on Serum Calcification Propensity in Subjects with End Stage Kidney Disease: A Randomized, Controlled Clinical Trial
Bressendorff, et al. Clin J Am Soc Nephrol. 2018;13(9):1373-1380

A preview of this infographic is available below, and can be downloaded to the left.
Code of conduct/disclaimer available in General Terms & Conditions

By clicking “Accept Terms & all Cookies” or by continuing to browse, you agree to the storing of third-party cookies on your device to enhance your user experience and agree to the user terms and conditions of this learning management system (LMS).

Cookie Settings
Accept Terms & all Cookies