Pregnancy related acute kidney injury: A slowly declining entity? Systematic review of data from Asia over a twenty-year period
ISN Academy. Nayak Rao S. Sep 14, 2018; 233299; 4701 Topic: Obstetrics & Pregnancy
Shobhana Nayak Rao
Shobhana Nayak Rao
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Acute kidney injury (AKI) in pregnancy is a rare but potentially lethal complication with often disastrous consequences for both the mother and child. It is largely preventable if regular antenatal care is provided and potentially responsible obstetric complications are recognised early. The incidence and mortality rates associated with obstetric AKI (also known as pregnancy-related AKI, PR-AKI) have decreased over the last few decades in the developed world, and are gradually reducing in developing countries as well. In 2013, the International Society of Nephrology (ISN) put forth the 0by25 human rights statement, which stated an objective of zero untreated AKI deaths in low resource regions by 2025, with an emphasis on resource-poor countries in Africa, Asia and Latin America. This will require a concerted effort as well as sufficient resource mobilization and training of all personnel involved. The prevailing incidence of PR-AKI in developed countries ranges from 1 in 10,000 to 20,000 pregnancies. In recent reports published in the Indian subcontinent, the frequency of obstetric AKI has been reported to vary between 4-15% and has shown a consistent downward trend. Along with a decline in incidence, there has also been a shift from septic abortion associated AKI to that associated with pre-eclampsia and puerperal sepsis. Our aim was to review this changing scenario of PR-AKI over the last two decades based on published data from Asia.


Author: Dr. Shobhana Nayak Rao, Associate Professor of Nephrology, KS Hegde Medical Academy, University Enclave, Derlakatte, Mangalore, India.

About Global Outreach Postings

Nephrologists from emerging countries had the opportunity to publish their manuscripts through the Global Outreach Postings Program. The aim of this initiative was to grant access to nephrologists from emerging countries to publish manuscripts in line with the ISN's mission and of interest to readers from around the world, including in emerging countries.

GOP articles were also published in the Open Urology & Nephrology Journal, an Open Access online journal published by Bentham OPEN, under a specific ISN heading and at no cost.

The GOP was discontinued to allow more focus for other emerging education initiatives, however those seeking research and writing mentorship are encouraged to apply for the ISN Mentorship Program.
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